2C-I

• Systematic (IUPAC) name : 2,5-Dimethoxy-4-iodophenethylamine
• CAS: 69587-11-7
• Formula: C₁₀H₁₄INO₂
• Mol. mass: 307.13 g/mol

2C-I or 2,5-dimethoxy-4-iodophenethylamine is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin. The drug is used recreationally for its psychedelic and entactogenic effects. 2C-I is commonly sold in its hydrochloride salt form, which is a fluffy, sparkling-white powder.In general, 2C-I is taken orally, although it can also be insufflated (though 2C-I often causes considerable pain upon insufflation) or administered rectally as well. It is also possible to smoke or vaporize it, although the dose required is higher. There have also been a few reports of intramuscular and intravenous injections. Intravenous doses should not be self-administered due to the immediate onset of hallucinations and strong physical stimulation before the needle's plunger is fully depressed. An oral recreational dose of 2C-I is commonly between 10 mg and 25 mg, although doses as low as 2 mg have been reported to be active.The onset of effects usually occurs within two hours, and the effects of the drug typically last somewhere in the range of 4 to 12 hours (depending on the dose). The effects of the drug at small dosages (less than 12 mg) has been reported as more mental and less sensory than those of 2C-B. Users of 2C-I do, however, tend to report a physical stimulant effect, often quite strong and clean. The effects of the drug at larger dosages (12-30+ mg) are often described as combining psychedelic or hallucinogenic effects typical of drugs such as LSD with the empathogenic or entactogenic effects of drugs such as MDMA (ecstasy). Although unpleasant physical side-effects such as muscle tension, nausea, and vomiting have been reported, their incidence with the use of 2C-I appears to be less common than with some closely related phenethylamines such as 2C-T-2 and 2C-T-7. Some physical effects include dilated pupils, high energy, and muscle relaxation. Users report feeling light and sometimes giddy or excited during the first two hours. Users also report that heavy music, usually electronic, and other auditory stimulation is enjoyable.